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W. Birchmeier Lab | MDC Berlin

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February 01, in Life Sci Alliance.

We show that different effector interactions with Gab1 play distinct biological roles downstream of Gab1 during the development of different organs. At Sex dating Delbrueck Long Night of the Sciences, visitors to the MDC will voyage through this fascinating cosmos in the company of experts.

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Our analysis contributes to a better understanding of the mechanisms of Schwann cell development and fate decisions. During zebrafish embryogenesis, BCL acts in the Wnt8-signaling pathway and regulates mesoderm patterning. Dok-4 and dok-5 Sex dating Delbrueck not associate with rasGAP or Nck, in contrast to p62dok and dok Our data thus demonstrate an essential role of Gab1 downstream of receptor tyrosine Sex dating Delbrueck Sex dating Delbrueck upstream of Shp2 and Mapk in the regulation of the hair cycle and the self-renewal of hair follicle stem cells.

We performed a high-throughput in silico screen for small-molecular-weight compounds that bind the catalytic site of Shp2.

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Taketo, E. Gab1 is a scaffold protein that acts downstream of receptor tyrosine kinases.
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Using primary cultured Schwann cells, we analyze the upstream effectors, Wnt and Rspondin ligands that initiate signaling, and downstream genetic programs that mediate the Wnt response. Wei et al.

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Delbrueck, North Rhine-Westphalia, Germany Latitude: 51.76.8.5654, Longitude: 298.293838939

Region time Europe/Berlin

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W. Birchmeier Lab
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